|
S. aromaticum |
O.
sanctum |
|
|
Toxic Dose |
Equal or greater than 1500 mg/kg [98] |
55 ml/kg [99] |
|
Maximum Daily Intake |
2.5 mg/kg[35] |
30 ml/kg [99] |
|
LD50 |
18.2 ±5.52 mg/ml in Danio rerio
and 21.7 ±0.8 mg/ml in Poecilia
reticulata at 96h[100] |
42.5 ml/kg 99] |
|
Adverse Reaction |
Spermicidal activity in males, allergic action when used in
dentistry, increased endogenous redox enzyme levels and
Reduced lipid peroxidation in humans resulted in disseminated
intravascular coagulopathy, generalized seizures, and hepatotoxicity,
detoxification, and cardiac health effects, allergic contact dermatitis in
guinea pigs[98] [101] |
Clinical
trial reporting transient moderate nausea [102] |